The slide includes a delta shaped slide or guide member or body having a central strip normally biased downwardly and pointing to the rear and terminating in a beveled hooked end. The underside of the body is provided with downwardly depending guides for slidable engagement with the opposing surfaces of a pair of rails carried by the channel, while the hooked end of the strip extends into the channel between the rails thereof. A stop member is carried on the channel near its outer wall in engageable relationship to the hooked end for positively limiting sliding movement of the body along the channel during the procedure of withdrawing the drawer, with the length of the hook being exposed so that it may be pressed upwardly to release and remove the drawer. The delta shaped body is provided with an upwardly extending rear flange for overlying the rear of the drawer.
Justia Patents Kenneth H. Gutner Kenneth H.It has, in fact, the double characteristic of being, on the one hand, an agonist of receptors of the melatoninergic system and, on the other hand, an antagonist of the 5-HT2C receptor. These properties provide it with activity in the central nervous system and, more especially, in the treatment of major depression, seasonal affective disorder, sleep disorders, cardiovascular pathologies, pathologies of the digestive system, insonmia and fatigue due to jet-lag, appetite disorders and obesity. Agomelatine, its preparation and its use in therapeutics have been described in European patent specifications EP 0 447 285 and EP 1 564 202. In view of the pharmaceutical value of this compound, it has been important to be able to produce it using an effective industrial synthesis process which is readily transferable to the industrial scale and which provides agomelatine in a good yield and with excellent purity. In patent specification EP 1 564 202, the Applicant developed a new, much more effective and industrialisable synthesis route in only four steps starting from 7-methoxy-1-tetralone that makes it possible to obtain agomelatine in highly reproducible manner in a well-defined crystalline form.
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